Western blotting revealed that compared with the sham group, KCNQ1 and KCNH2 protein levels were decreased to 48 and 20%, respectively, in the ischemic myocardium of the MI group (Fig. 4; all P < 0.05); t-AUCB reversed these changes. The gene discussed is KCNH2; the disease is myocardial infarction.