GMDS and lung adenocarcinoma: Without fresh specimens in hand, we further examined GMDS expressions using immunohistochemistry with only one suitable antibody with tissue microarray and confirmed the upregulation of GMDS expression at protein level in human lung adenocarcinoma, with GMDS protein density at 3.597 ± 1.908 in human lung adenocarcinoma and 0.453 ± 1.119 in adjacent normal tissues (Fig. 1c-d).