For example, misregulation of splicing caused by splicing factor Serine And Arginine Rich Splicing Factor 1 (SRSF1) can lead to the malignant transformation of normal mammary cells [5]; we also reported that Serine And Arginine Rich Splicing Factor 6 (SRSF6) promotes tumor progression by regulating AS and might be a potential therapeutic target [6]. The gene discussed is SRSF1; the disease is neoplasm.