For example, carcinogenesis is closely associated with reactive oxygen species (ROS) which cause DNA damage and activate nuclear factor-κB (NFκB) which modulates the expression of cancer-associated cytokines such as the tumor necrosis factor (TNF)α and enzymes such as cyclooxygenase (COX) and matrix metalloproteinases (MMPs) [1]. The gene discussed is NFKB1; the disease is cancer.