CDH5 and pulmonary arterial hypertension: found that urinary CD144+/AV+ EMV levels were increased in PAH patients compared with controls and that CD144+/AV+ EMVs were directly correlated with tricuspid annular plane systolic excursion (TAPSE) in PAH patients.47 Therefore, urinary CD144+/AV+EMVs may be useful as potential biomarkers of right ventricular function in PAH.