PECAM1 and pulmonary emphysema: Furthermore, Gordon et al.26 demonstrated that EMVs could represent a potential marker of early emphysema; a low ratio of CD62E+ to CD31+ EMVs indicates a high percentage of apoptotic EMVs in early emphysema, while the presence of angiotensin‐converting enzyme on the surface of most EMVs indicates a pulmonary capillary origin.