TGF‐β1 signalling is a well‐known pathway that could induce CMT and promotes myocardial fibrosis.4 On the other hand, recent studies indicate that Notch signalling inhibits CMT and alleviates myocardial fibrosis.18, 19 However, the underlying mechanism by which TGF‐β1 and Notch signalling pathways crosstalk to regulate CMT remains not fully understood. This evidence concerns the gene TGFB1 and Myocardial fibrosis.