APOE and atherosclerosis: Notably, clearing senescent cells using either genetic approaches or senolytic drug treatments limits the development of atherosclerosis in the Ldlr−/− (Childs et al., 2017) or the APOE−/− (Wang et al., 2015) mouse models, a mechanism which is consistent with the phenotype of the subordinate mice and suggests a possible senescence‐associated link between stress and atherosclerosis.