MPO and pulmonary aspergilloma: In lung aspergillosis mouse model, compared with untreated aspergillosis mice, expression of NLRP3 mRNA was significantly decreased in mice intraperitoneally injected with IL-37, while levels of myeloperoxidase (Mpo), CxCl2, IL-1β, IL-17A, and IFN-γ were significantly reduced [16].