IL6 and systemic lupus erythematosus: Song et al. [58] found that serum level of IL-37 was significantly higher in patients with SLE than in healthy controls, and IL-37 level decreased after treatment with glucocorticoid, and IL-37 level was positively correlated with IL-18, IL-18BP, IFN-γ, IL-6, and SLEDAI score before and after treatment [58].