IL37 and Hyperkalemia: Nold et al. [3] found that, compared with wild-type mice, alleviated inflammatory response, weakened LPS-induced hypothermia, metabolic acidosis, dehydration, hyperkalemia symptoms and liver injury and other endotoxic shock performance, and increased respiratory compensation were observed in mice transplanted with human IL-37 precursor gene (transgenic mice for human IL-37 precursor, hIL-37tg) after intraperitoneal injections of LPS.