IL-37 expression has been detected in human tissues such as liver, lung, thymus, bone marrow, lymph nodes, placenta, testis, uterus, and tumor tissue and in human cell lines such as A431, THP-1, U937, IMTLH, KG-1, HL60, HPBMC, HPT-4, and NHDC [13]. The gene discussed is IL37; the disease is neoplasm.