AAV, ANCA-associated vasculitis; ANCA, antineutrophil cytoplasmic antibody; F, female; M, male; AA, African American; CA, Caucasian; OT, other; MPO, myeloperoxidase; PR3, anti-proteinase; NEG, negative; S, sinus; J, joints; L, lungs; K, kidneys; SK, skin; P, peripheral nerves; PID, patient identification. The gene discussed is PRTN3; the disease is anti-neutrophil cytoplasmic antibody-associated vasculitis.