ROS1 fusion has been reported in glioblastoma multiforme [3, 4], non-small cell lung cancer (NSCLC) [5], cholangiocarcinoma [6], gastric cancer [7], and colorectal cancer [8], and NTRK fusion proteins have been reported in thyroid carcinoma [9], colorectal cancer [10], melanoma [11], breast cancer [12], and NSCLC [13, 14]. This evidence concerns the gene ROS1 and colorectal cancer.