Other pathways such as the endoplasmic reticulum (ER) stress pathway, not involved in the 8 leukemogenesis-related coupling STPs (Supplementary Figure 1), have been also suggested to participate in the induction of transcriptional regulation by C/EBPα in AML and MDS leukemogenesis [31, 32]. This evidence concerns the gene CEBPA and myelodysplastic syndrome.