Although most tumors were MPNSTs (Figure 2D–2E), 25% (6 out of 24) of tumors were peripheral primitive neuroectodermal tumors (pPNETs, Figure 2F–2G) in sdpw12/+;rpL35hi258/+, while only 7% (2 out of 28) were pPNETs in rpL35hi258/+, suggesting that the reck gene may have a cell type differential role during tumor formation. The gene discussed is RECK; the disease is neoplasm.