Our results support the emergent role of the spliceosome pathway in prostate carcinogenesis [39] with TRA2A and U2AF1: TRA2A is deregulated in different cancers such as hepatocellular carcinoma, pediatric pineal germinomas and triple-negative breast cancer (TNBC) [40–42]. The gene discussed is U2AF1; the disease is triple-negative breast carcinoma.