Thus, the measurement of serum CA-125 is still commonly used as the index of ovarian cancer even though a variety of benign gynecological and nongynecological conditions also increase the level of CA-125 including endometriosis, functional ovarian cysts, pelvic inflammation, cirrhosis, colitis, renal disease, tuberculosis, and pregnancy [2, 3]. Here, MUC16 is linked to ovarian carcinoma.