Increased IL-10 has been linked to atypical antipsychotic treatment in mouse models exposed to lipopolysaccharide (LPS) and polyinsinic-polycytidylic acid (Poly I:C) [50], as well as in vitro studies using Poly I:C stimulated blood samples from patients with schizophrenia [51]. This evidence concerns the gene IL10 and schizophrenia.