Quantification of cells which had invaded through Matrigel, showed that knockdown of PTTG3P decreased the number of invaded cells in both HepG2 and Hep3B cells whereas over-expression of PTTG3P had opposite effects(Fig. 5b).Thus, these data suggest that lncRNA PTTG3P induces HCC cell migration and invasion in vitro. Here, PTTG3P is linked to hepatocellular carcinoma.