At the univariate level, the mean intrusion and avoidance scores on the IES scale were significantly higher in both BRCA1 and BRCA2 mutation carriers compared with controls (intrusion: P = 0.001; avoidance: P < 0.001; Table 2) and higher in those who perceived their PCa risk as moderately or strongly increased (intrusion: P < 0.001, avoidance: P = 0.001; Table 3); however, at the multivariate level, risk perception contributed more significantly to the variation in IES scores than genetic status (Table 4). The gene discussed is BRCA2; the disease is posterior cortical atrophy.