IL-6 expression is altered in the brains of AD patients; it is elevated around amyloid plaques and in the CSF (Bauer et al. 1991; Strauss et al. 1992; Wood et al. 1993; Hull et al. 1996; Hampel et al. 2005; Cojocaru et al. 2011). The gene discussed is IL6; the disease is Alzheimer disease.