MOV10L1 and coronary artery disorder: One of the novel recurrent epivariations detected only in our patient cohort was found in two patients with CHD (Probands 22 and 117), and represents a recurrent hypo-methylation defect at the promoter—5′ UTR—first exon of MOV10L1, a gene with an embryonic heart-specific isoform that interacts with the master cardiac transcription factor NKX2.513 (Fig. 1).