In the meanwhile, HK L-137 exhibited a tendency to attenuate the increase in the amount of phosphorylated form of p65 subunit of nuclear factor-kappa B (NF-κB) in the MetS group (P = 0.09 versus MetS + HD, P = 0.07 versus MetS + LD; Fig. 3L). Here, NFKB1 is linked to metabolic syndrome.