Other commonly mutated genes in ARVC include DSG2 (Desmoglein 2), DSP (Desmoplakin), DSC2 (Desmocollin 2) and JUP (Junction Plakoglobin), which cause the disease mainly in the autosomal dominant mode, apart from the JUP gene and sometimes DSP, DSC2 and more recently DSG2 genes, where variants cause recessive ARVC [14–16]. The gene discussed is DSC2; the disease is arrhythmogenic right ventricular cardiomyopathy.