This is a similar pattern to that observed between the other two major GBM subtypes, where telomerase-positive, IDHWT-TERTpMUT GBMs exhibit significantly higher TERT mRNA expression (P = 0.0036, Kruskal–Wallis test using Dunn’s test post hoc) relative to the IDHMUT-TERTpWT GBMs, which are ATRX mutated and exhibit ALT10. The gene discussed is ATRX; the disease is glioblastoma.