SLC5A2 and type 2 diabetes mellitus: Januzzi et al. [1] reported that treatment with canagliflozin, a sodium glucose co-transporter 2 (SGLT2) inhibitor, attenuated serial escalation of cardiovascular (CV) biomarkers, including N-terminal pro-B type natriuretic peptide and high-sensitivity troponin I, over a 104-week period compared with placebo, in older adults with type 2 diabetes (T2D).