In summary, we identified particular differentiation stages of dysplastic hematopoiesis at which CLL-1, CD44, and CD47 were aberrantly expressed and at which ALDH was downregulated in MDS-EB and we showed that the myeloid markers CD13/CD33 were aberrantly expressed on CMPs and MEPs in both low-risk and MDS-EB patients (Fig 6). This evidence concerns the gene CD33 and epidermolysis bullosa.