DEPTOR and chronic obstructive pulmonary disease: Subsequent analysis, stratified by disease state, identified three SNPs nominally associated with k in moderate-to-severe COPD only (rs6481619 within SVIL, EAF = 0.746, β = 0.152, P = 0.013; BTAF1, EAF = 0.798, β = 0.196, P = 0.046, I2 = 41.6; Het_P = 0.191; rs7386139 within DEPTOR, EAF = 0.219, β = 0.159, P = 0.047; Appendix 2, Supplemental Tables S4 and S5).