KLF10 and Sepsis: Moreover, transcriptomic analysis of peritoneal cells in a mouse model of sepsis caused by infection with a non-pathogenic strain of Escherichia coli revealed that KLF10 was down-regulated at 2 h [45], while KLF10 induces TGF-β1 expression, which is an anti-inflammatory cytokine and regulates T cell activation [29].