Remarkably, the present study identifies some segments immediately adjacent to known PD-related genes, i.e., the segment on chromosome 4 (4q21.1) that in the TRAM FEMALE analysis (Table 5), was shown to be adjacent to the one comprising the SNCA gene (PARK1/PARK4), encoding for alpha-synuclein. The gene discussed is SNCA; the disease is Parkinson disease.