The average model performances (AUC, Sensitivity, Specificity) using a univariate logistic regression model with mean ALT over 96 weeks showed better performance for NASH (85.6 (9.3); 71.1 (15.7); 84.4 (10.7)) and NASH + fibrosis assessments (84.9 (8.6); 67.9 (16.8); 85.7 (11.2)) than fibrosis (69.6 (10.4); 62.9 (12.5); 70.9 (14.6)) and NAS (65.1 (10.7); 57.9 (12.4); 64.6 (16.4)). This evidence concerns the gene GPT and metabolic dysfunction-associated steatohepatitis.