Similarly, the univariate logistic regression indicated that percent change in ALT (at week 96 compared to baseline) was also a significant predictor of progression of NAFLD for each histologic assessment (p < 0.001 for NAS, NASH, and NASH + fibrosis and p < 0.01 for fibrosis score). The gene discussed is GPT; the disease is metabolic dysfunction-associated steatohepatitis.