MPO and Pancytopenia: Diagnosis relies on laboratory findings showing pancytopenia or hyperleukocytosis in around 20% (complete blood cell count with differential cell counts), bone marrow examination that shows large blasts, numerous granules, Auer rods often in bundles, faggot cells, promyelocytic cells, and strong positive on myeloperoxidase staining, bone marrow histology and on coagulation status [7].