KIT and small cell lung carcinoma: Our data from the ER-ve MDA-MB-231 supports a model in which the glycolytic SCLC cells can take on characteristics of either c-KIT+ve early progenitors or c-KITlow late progenitors, whereas under glycolysis-restricted conditions they are more constrained to the c-KIT+ve early progenitor-like state and are therefore more c-KIT dependent.