EPAS1 and renal cell carcinoma: To clarify the contribution of TNFSF10 in the mechanism of cell death induced by knockdown of HIF2-alpha in dormant-like/starvation-resistant RCC, siRNA for TNFSF10 (siTRAIL) was introduced into all three dormant-like/starvation-resistant RCCs, accompanied by siRNA for HIF2-alpha (siHIF2).