ACE and cardiovascular disorder: Based on major practice guidelines from the National Institutes of Health and updated ACCF/AHA practice guidelines, and results from recent clinical trials, AHA/ACCF guideline recommends four medicines for the secondary prevention of cardiovascular disease including Aspirin, β blockers, Angiotensin-converting enzyme (ACE) inhibitors or Angiotensin-II receptor blockers (ARBs), and Statins.