PLAT and brain infarction: Brain infarct volumes (corrected for edema) were 35.6 ± 2.0 mm3 in the BSA group, 18.7 ± 4.2 mm3 in the prHSP27 group, 38.0 ± 4.6 mm3 in the tPA group, and 31.2 ± 4.0 mm3 in the tPA plus prHSP27 group (Fig 1D).