KLK3 and posterior cortical atrophy: Crook et al described the outcomes of patients who underwent IAD for PSA recurrence after PCa radiotherapy; the authors reported a median overall survival of 8.8 and 9.1 years in the IAD and CAD groups, respectively, with no significant difference between the two groups (HR 1.02; 95% confidence interval 0.86–1.21) [10].