BAD and Sepsis: Under conditions of CLP-induced high-grade sepsis, a significant amount of non-phosphorylated BAD translocated to mitochondria in the liver of WT littermate (Fig. 6a, ~27%, 12 h), even though a similar amount of BAD was simultaneously phosphorylated by IKK at Ser26 (Fig. 6a, 32%, 12 h).