Particularly for T2D, VDR may act as a transcription factor for \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\beta $$\end{document}β cell insulin secretion regulation, thereby affecting lipid metabolism46. Here, INS is linked to type 2 diabetes mellitus.