The CD30 immunostaining intensity was graded as: weak in 14 cases of UP/MPCM and in one case of solitary mastocytoma of skin, moderate in 6 cases of UP/MPCM, in one case of diffuse cutaneous mastocytosis and mastocytoma of skin each, strong in 2 cases of UP/MPCM and in one case of diffuse cutaneous mastocytosis. Here, TNFRSF8 is linked to mastocytoma.