Patients with advanced TNM stage (III/IV) or tumor size larger than 30 mm were associated with higher AFAP1-AS1 expression, whereas patients with local TNM stage (I/II) or tumor size smaller than 30 mm were associated with lower AFAP1-AS1, respectively (Fig. 1b, P =0.046) (Fig. 1c, P =0.039). The gene discussed is AFAP1; the disease is neoplasm.