ZNF346 and neuroblastoma: To figure out the molecular mechanisms in which the miR-1247 regulates cell proliferation and apoptosis in NB, we searched for potential target genes of miR-1247 using three tool databases including TargetScan (www.targetscan.org), miRpathDB (https://mpd.bioinf.uni-sb.de/), and microRA.org (http://www.microrna.org/), and found ZNF346 gene was predicted as a putative target for miR-1247, which might be implicated in the pathogenesis of NB (Fig. 5a).