CSNK1A1 and familial pancreatic carcinoma: Likewise, ABC DLBCL requires CK1α for constitutive NF-κB activity and survival; lenalidomide may have therapeutic effects in ABC DLBCL by inducing the degradation of CK1α [11, 12, 172], as well as in pancreatic cancer in which CK1α is upregulated.