These differences pressed us to directly compare prenatal PTSD and TE groups, for which we found a number of under-expressed genes in PTSD (over-expressed in TE) significantly related to (P < 0.05) corticotropin-releasing hormone (CYP11A1, FOSB, RAF1) and circadian rhythm (NOS2, LEP, CSNK1E) and over-expressed genes in PTSD (under-expressed in TE) related to cytoskeleton remodeling (RSU1, LIMS1) and interferon signaling (OAS1, STAT2, XAF1) (Supplementary Table 2). The gene discussed is CRH; the disease is post-traumatic stress disorder.