DRD2 and schizophrenia: The result of the analysis of the factor associated with the -141Cvariant of the DRD2 and rs6280 genes, component ofthe syndrome, low HDL, is shown in Table 5.The homozygous genotype for the Ins C allele of the -141Cpolymorphism (OR: 19.8) was associated with low HDL, that is, in this study, it wasevidenced that a patient diagnosed with refractory schizophrenia who presented the-141C variant of the DRD2 gene and had thehomozygous genotype for the Ins C allele was almost 20-fold more likely to present alow HDL level when compared to the heterozygous genotype.