Finally, Quintavalle et al [32] assessed the role of urine NGAL and serum NGAL at 2, 6, 24, and 48 hours after contrast media exposure for CI-AKI detection (defined as SCr increase ≥0.3 mg/dl) in 458 high-risk patients (GFR ≤ 30 ml/min) undergoing coronary or peripheral angiography or angioplasty. The gene discussed is LCN2; the disease is acute kidney injury.