HOTAIR and hepatocellular carcinoma: Long noncoding RNAs (lncRNAs), a class of noncoding transcripts with the length of more than 200 nucleotides, have been recognized as functional fragments in many biological processes by targeting related genes.6 So far, several HCC‐related lncRNAs, such as HULC, HOTAIR, and MALAT1, have been identified, whose dysregulation can responsible for HCC pathogenesis partially through regulating cell proliferation and apoptosis, angiogenesis, and tumor metastasis.7 On the other hand, lncRNAs are studied widely as key regulators of lipid metabolism.