The oval inclusion bodies seen on LC3A, but only infrequently on LAMP‐2, and not at all on LAMP‐1, CTSD and EEA‐1, immunostaining in DG in those cases of FTLD‐tau associated with Pick bodies (Pick's disease) are likely to be Pick bodies, since these are well known to cluster in neurones of the dentate gyrus, CA1 and pyramidal neurones of the frontal and temporal cortex 55. This evidence concerns the gene PICK1 and frontotemporal dementia.