The patients with Ki67 6–20% more frequently had lymph node metastases (53 vs 22%; p = 0.0002), perineural invasion (28 vs 11%; p = 0.0129), vascular invasion (51 vs 20%; p < 0.0001), and R1 resection (36 vs 12%; p = 0.0438) than the patients with Ki67 0–5%. This evidence concerns the gene MKI67 and metastatic malignant neoplasm in the lymph nodes.