PIR and Cirrhosis: The top five differentially upregulated piRNAs in cirrhosis (Table 7) were: piR-32299 (7658-fold), piR-28488 (2105-fold), piR-7239 (1497-fold), piR-5939 (536-fold), and piR-5067 (106-fold); whereas, the top five downregulated were: piR-952 (423-fold), piR-28525 (140-fold), piR-5938 (87-fold), piR-5937 (65-fold), and piR-25780 (49-fold).