IL22 and Helicobacter pylori infectious disease: No significant difference in mRNA expression of gastric Il-22 between H. pylori-infected and control B6 mice at 16 WPI in this study was consistent with a previous report showing that H. pylori-induced elevation of gastric Il-22 transcription in BALB/c and B6 mice peaked at 35 days after H. pylori infection and then was decreased to the same level as uninfected controls by 2 months after H. pylori infection25.