ALKBH5 and viral infectious disease: ALKBH5 is expressed in most tissues, being particularly abundant in the testes where it impacts mouse spermatogenesis and fertility.17 ALKBH5 regulates splicing and stability of mRNAs in the nuclei of spermatocytes and round spermatids by removing m6A from pre-mRNAs and allows the production of mRNAs containing longer 3’UTRs.95 Moreover, ALKBH5 plays an important role in the immune response to viral infections in macrophages.