Sequencing using a custom panel with genes linked to ALS/FTD and Alzheimer revealed a heterozygous Q108P mutation in CHCHD10, but no mutations in APP, CSF1R, CHMP2B, FUS, GRN, HNRNPA1, HNRNPA2B1, MAPT, MATR3, NEK1, OPTN, PSEN1, PSEN2, SOD1, TARDBP, TBK1, TUBA4A, TREM2, or VCP (see Materials and Methods). Here, MATR3 is linked to frontotemporal dementia.