SOD1 and amyotrophic lateral sclerosis: ALS‐causing mutations in SOD1 inhibit respiration and cause mitochondrial damages (Magrane et al, 2009), and poly‐Gly‐Arg/Pro‐Arg translated from the expanded C9orf72 hexanucleotide repeat induce oxidative stress and disrupt mitochondrial architecture (Lopez‐Gonzalez et al, 2016).